Benefits of CBD and Other Cannabinoids in Health and Skin Care Based on Scientific Evidence and Applications in Pharma Dream

Cannabidiol (CBD) and other cannabinoids have emerged as promising compounds in medicine, dermatology, and general wellness. Unlike THC, CBD is non-psychoactive, and its therapeutic properties are supported by preclinical and clinical studies. In this article, we explore the scientifically validated benefits of CBD and other cannabinoids, along with their integration into innovative cosmetic products like those from Pharma Dream , which combine science, nature, and molecular extraction technology.

1. The Endocannabinoid System (ECS): The Biological Basis

The human body has an endocannabinoid system (ECS) , composed of receptors (CB1 and CB2), endocannabinoids, and enzymes. This system regulates functions such as pain, inflammation, sleep, appetite, and skin homeostasis. Cannabinoids like CBD interact with the ECS, modulating these functions without altering mental state.

Key Study :

Demonstrates how CBD acts as an allosteric modulator of CB1/CB2 receptors, explaining its anti-inflammatory and analgesic effects.

Pertwee, R. G. (2008) . The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-THC, CBD, and CBG . British Journal of Pharmacology.

2. CBD Benefits Validated by Science

A. Anti-inflammatory and Analgesic Properties

CBD reduces inflammation by inhibiting the production of proinflammatory cytokines (such as TNF-α and IL-6) and activating vanilloid receptors (TRPV1), associated with pain perception.

• Key Study :
  • Nagarkatti, P. et al. (2009) . Cannabinoids as novel anti-inflammatory drugs . Future Medicinal Chemistry.
    • It confirms the potential of CBD to treat chronic inflammatory diseases, such as rheumatoid arthritis.

B. Antioxidant and Anti-aging Effects

CBD neutralizes free radicals (ROS), preventing oxidative damage that accelerates skin aging. It also stimulates collagen and elastin synthesis.

• Key Study :
  • Atalay, S. et al. (2020) . Antioxidative and Anti-Inflammatory Properties of Cannabidiol . Antioxidants.
    • Highlights CBD's ability to reduce oxidative stress in skin exposed to UV and pollution.

C. Sebum and Acne Regulation

CBD inhibits lipogenesis in the sebaceous glands, balancing sebum production and reducing acne breakouts.

• Key Study :
  • Oláh, A. et al. (2014) . Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes . Journal of Clinical Investigation.
    • CBD normalizes sebum production and reduces inflammation in human sebaceous cells.

D. Anxiety and Sleep

CBD modulates the activity of serotonin (5-HT1A) and GABA receptors, reducing anxiety and improving sleep quality.

• Key Study :
  • Blessing, E.M. et al. (2015) . Cannabidiol as a Potential Treatment for Anxiety Disorders . Neurotherapeutics.
    • Reviews preclinical evidence supporting the use of CBD in anxiety disorders.

3. Other Relevant Cannabinoids

A. Cannabigerol (CBG)

• Properties : Antibacterial, neuroprotective and hair growth stimulant.
• Key Study :
  • Borrelli, F. et al. (2013) . Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease . Biochemical Pharmacology.
    • CBG reduces intestinal inflammation in animal models.

B. Cannabinol (CBN)

• Properties : Mild sedative and promoter of bone healing.
• Key Study :
  • Wong, H. et al. (2019) . Cannabinol enhances osteoblast differentiation . Journal of Cellular Physiology.
    • CBN stimulates bone cell formation in in vitro studies.

4. Applications in Pharma Dream: CBD and Cosmetic Science

A. Molecular Extraction Technology

Pharma Dream uses advanced extraction methods (phytomolecular extraction) to isolate cannabinoids and phytonutrients without degrading them. This guarantees:

• High bioavailability : The CBD in the Revitalizing Serum penetrates the dermis.
• Botanical synergy : Combination with witch hazel, calendula and aloe vera to enhance effects.

B. Featured Products

1. Micellar Water with CBD :
   • Benefit : Anti-inflammatory cleansing and pH regulation (supported by Oláh et al., 2014).
2. CBD Facial Cream :
   • Benefit : Sebum control and prevention of clogged pores (JCI, 2014).
3. Sunscreen SPF50 with CBD :
   • Benefit : UV protection + antioxidant repair (Atalay et al., 2020).

Scientific References

1. Pertwee, R. G. (2008). British Journal of Pharmacology . Link .
2. Oláh, A. et al. (2014). Journal of Clinical Investigation . Link .
3. Atalay, S. et al. (2020). Antioxidants . Link .
4. Blessing, E.M. et al. (2015). Neurotherapeutics . Link .

Frequently Asked Questions

Is CBD addictive?
No. The WHO does not classify CBD as an addictive substance.

Can I use CBD products alongside medications?
Consult your doctor. CBD may interact with liver enzymes (cytochrome P450).

Do Pharma Dream products contain THC?
No. They meet the legal limit of <0.3% THC, with no psychoactive effects.

CBD and other cannabinoids represent an innovative frontier in health and skin care, backed by rigorous scientific evidence. At Pharma Dream, we leverage these advances with ethical, sustainable formulas designed to enhance natural beauty. The combination of Colombian biodiversity and cutting-edge technology allows us to offer products that not only care, but also transform.